Publications by authors named "D F Pauly"

Neuromyelitis optica spectrum disorder (NMOSD) is associated with pathological aquaporin-4 immunoglobulin G (AQP4-IgG), which cause brain damage. However, the impact of AQP4-IgG on retinal tissue remains unclear. Additionally, dysregulated complement anaphylatoxins C3a and C5a, known to modulate the endothelial barrier, are implicated in NMOSD.

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Article Synopsis
  • Aquacultured carnivorous species heavily rely on fishmeal and fish oil, mostly sourced from small pelagic fish, raising concerns about their impact on wild fish stocks and coastal communities.
  • The aquaculture industry uses the Fish In:Fish Out (FIFO) metric to claim reduced dependency on wild fish, but this metric is misleading due to fluctuating yields and varying feed requirements.
  • The increasing use of FMFO from by-products is a sign of rising demand, especially in salmon and shrimp farming, rather than a reduction in wild fish usage.
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Current stock assessment models overestimate productivity and recovery trajectory.

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