Dementia Care Research and Psychosocial Factors.

Background: Asian American, Native Hawaiian, and Pacific Islander (AANHPI) populations are underrepresented in Alzheimer's disease and related dementias (ADRD) research, despite being the fastest growing racial group in the United States. The Collaborative Approach for AANHPI Research and Education (CARE) registry aims to create a sustainable research recruitment source to address this need.

Method: Participants can enroll online, by phone, or in-person by completing an enrollment survey in English, Chinese (Simplified/Traditional), Hindi, Korean, Samoan, or Vietnamese.

Dementia Care Research and Psychosocial Factors.

Background: The Collaborative Approach for Asian Americans, Native Hawaiians, and Pacific Islanders (AANHPI) Research and Education (CARE) is a recruitment registry that has enrolled over 10,000 AANHPI participants who expressed willingness to participate in Alzheimer's disease and related dementias (ADRD), aging, caregiving, and other health research. We report survey results from 24 of the 28 study principal investigators ("users") who utilized CARE between January 2021 and October 2023 to support their study recruitment.

Method: Users answered five questions on a 4-point Likert scale (0 = Strongly disagree to 3 = Strongly agree) related to (1) user experience, (2) usefulness in accelerating recruitment, (3) improving AANHPI representation, (4) whether they would use the registry again, and (5) whether they would recommend the registry to others.

Unlocking the Hidden Potential of Cancer Therapy Targeting Lysine Succinylation.

Lysine succinylation is an emerging post-translational modification of proteins. It involves the addition of the succinyl group to lysine residues of target proteins through both enzymatic and non-enzymatic pathways. This modification can alter the structure of the target protein, which, in turn, impacts protein activity and function and is involved in a wide range of diseases.

Prognostic significance of MRD and its correlation with arsenic concentration in pediatric acute promyelocytic leukemia: a retrospective study by SCCLG-APL group.

Background: Treatment outcomes for acute promyelocytic leukemia (APL) have improved with all-trans-retinoic acid and arsenic trioxide, yet relapse remains a concern, especially in pediatric patients. The prognostic value of minimal residual disease (MRD) post-induction and the impact of arsenic levels during induction on MRD are not fully understood.

Objectives: To evaluate the relationship between post-induction MRD levels and relapse-free survival (RFS) in pediatric APL patients, and to investigate the correlation between blood arsenic concentration levels during induction therapy and MRD status.

A Chain Entanglement Gelled SnO₂ Electron Transport Layer for Enhanced Perovskite Solar Cell Performance and Effective Lead Capture.

SnO₂ is a widely used electron transport layer (ETL) material in perovskite solar cells (PSCs), and its design and optimization are essential for achieving efficient and stable PSCs. In this study, the in situ formation of a chain entanglement gel polymer electrolyte is reported in an aqueous phase, integrated with SnO₂ as the ETL. Based on the self-polymerization of 3-[[2-(methacryloyloxy)ethyl]dimethylammonium]propane-1-sulfonic acid (DAES) in an aqueous environment, combining the catalytic effect of LiCl (as a Lewis acid) with the salting-out effect, and the introduction of polyvinylpyrrolidone (PVP) as the other polymer chain, a chain entanglement gelled SnO (G-SnO) structure is successfully constructed with a wide range of functions.