Peripheral Arterial Perfusion: Is it Adequate for Wound Healing?

 Peripheral arterial occlusive disease (PAOD) can seriously inhibit or prevent healing of lower extremity and foot ulcerations. The history and physical findings consistent with PAOD are reviewed and the typical characteristics of ischemic, venous, and neuropathic ulcerations are compared and contrasted. Noninvasive diagnostic testing techniques currently used to confirm the diagnosis of PAOD are summarized.

Effect of anaerobiosis on staphylococcal nuclease production.

Five strains of Staphylococcus aureus were examined quantitatively for the production of nuclease under aerobic and anaerobic conditions. Hydrolysis of deoxyribonucleic acid and ribonucleic acid was detected by measuring the release of acidsoluble nucleotides spectrophotometrically. We found that the enzyme was produced anaerobically, as well as aerobically, and that anaerobiosis had no effect on production of this enzyme when other conditions, such as pH, were held constant.