Fecal microbiota transplantation: transitioning from chaos and controversial realm to scientific precision era.

With the popularization of modern lifestyles, the spectrum of intestinal diseases has become increasingly diverse, presenting significant challenges in its management. Traditional pharmaceutical interventions have struggled to keep pace with these changes, leaving many patients refractory to conventional pharmaceutical treatments. Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic approach for enterogenic diseases.

Inactivation of antibiotic resistant bacteria by nitrogen-doped carbon quantum dots through spontaneous generation of intracellular and extracellular reactive oxygen species.

The widespread antibiotic resistance has called for alternative antimicrobial agents. Carbon nanomaterials, especially carbon quantum dots (CQDs), may be promising alternatives due to their desirable physicochemical properties and potential antimicrobial activity, but their antimicrobial mechanism remains to be investigated. In this study, nitrogen-doped carbon quantum dots (N-CQDs) were synthesized to inactivate antibiotic-resistant bacteria and treat bacterial keratitis.

Circulating molecules reflect imaging biomarkers of hemorrhage in cerebral cavernous malformations.

Increases in mean lesional iron content by quantitative susceptibility mapping (QSM) by ≥6% and/or vascular permeability by dynamic contrast enhanced quantitative perfusion (DCEQP) by ≥40% on MRI have been associated with new symptomatic hemorrhage (SH) in cerebral cavernous malformations (CCMs). It is not known if plasma biomarkers can reflect these changes within the lesion proper. This cohort study enrolled 46 CCM patients with SH in the prior year.

Angle-independent topological interface states in one-dimensional photonic crystal heterostructures containing hyperbolic metamaterials.

Topological interface states (TISs), known for their distinctive capabilities in manipulating electromagnetic waves, have attracted significant interest. However, in conventional all-dielectric one-dimensional photonic crystal (1DPC) heterostructures, TISs strongly depend on incident angle, which limits their practical applications. Here, we realize an angle-independent TIS in 1DPC heterostructures containing hyperbolic metamaterials (HMMs) for transverse magnetic polarized waves.

Facile Synthesis of Novel Conducting Copolymers Based on N-Furfuryl Pyrrole and 3,4-Ethylenedioxythiophene with Enhanced Optoelectrochemical Performances Towards Electrochromic Application.

In this article, a series of novel conducting copolymers P(FuPy--EDOT) are prepared via cyclic voltammetry electropolymerization method by using N-furfuryl pyrrole (FuPy) and 3,4-ethylenedioxythiophene (EDOT) as comonomers. The molecular structure, surface morphology, electrochemical, and optical properties of the resulting copolymers are characterized in detail upon varying the feed ratios of FuPy/EDOT in the range of 1/1 to 1/9. The results demonstrate that the prepared P(FuPy--EDOT) copolymers with a higher proportion of EDOT units (FuPy/EDOT: 2/8~1/9) possess good redox activity, tunable optical absorption performances, and low band gaps (1.