Publications by authors named "D F Carmichael"

Introduction: Intensive psychiatric care units can be challenging environments in which to build strong staff-patient relationships. Attachment theory may provide a useful model for strengthening relationships in this setting.

Aim: The aim of this study was to explore staff perceptions of the utility of attachment theory for understanding patient behaviour in the intensive psychiatric care setting.

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Purpose: Low-field (LF) MRI scanners are common in many Low- and middle-Income countries, but they provide images with worse spatial resolution and contrast than high-field (HF) scanners. Image Quality Transfer (IQT) is a machine learning framework to enhance images based on high-quality references that has recently adapted to LF MRI. In this study we aim to assess if it can improve lesion visualisation compared to LF MRI scans in children with epilepsy.

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Article Synopsis
  • A significant portion of epilepsy patients still experience seizures despite treatment, prompting exploration of transcranial direct current stimulation (tDCS) as a potential supplementary therapy for genetic generalized epilepsy (GGE).
  • A study involved both healthy controls and GGE patients receiving tDCS while undergoing fMRI, assessing its effects on sensorimotor cortex connectivity through three stimulation types: anodal, cathodal, and sham.
  • Results indicated that tDCS was safe and well-tolerated, with anodal and cathodal stimulation leading to a notable decrease in sensorimotor network connectivity, while the sham condition showed no significant differences compared to rest.
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There are considerable gaps in our understanding of the relationship between human brain activity measured at different temporal and spatial scales. Here, electrocorticography (ECoG) measures were used to predict functional MRI changes in the sensorimotor cortex in two brain states: at rest and during motor performance. The specificity of this relationship to spatial co-localisation of the two signals was also investigated.

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