Using linked administrative and census data for migration research.

Migration is a core component of population change and is both a symptom and a cause of major economic and social phenomena. However, data limitations mean that gaps remain in our understanding of the patterns and processes of mobility. This is particularly the case for internal migration, which remains under-researched, despite being quantitatively much more significant than international migration.

Risk factors for variant Creutzfeldt-Jakob disease in dental practice: a case-control study.

Objective: To assess the risk of variant Creutzfeldt-Jakob Disease (vCJD) associated with dental treatment.

Design: Case-control study, investigation of links between cases.

Setting: National CJD surveillance, general dental practice and practice boards in Great Britain, 2008-2009.

The role of cerebrospinal fluid 14-3-3 and other proteins in the diagnosis of sporadic Creutzfeldt-Jakob disease in the UK: a 10-year review.

Background: It is 10 years since the detection of cerebrospinal fluid (CSF) 14-3-3 was included in the diagnostic criteria for sporadic Creutzfeldt-Jakob disease (sCJD) by the WHO. Since that time, other CSF proteins, such as S100b and tau protein, have been proposed as surrogate markers for sCJD. The authors aimed to investigate the diagnostic value of each of these three proteins.

Risk factors for sporadic Creutzfeldt-Jakob disease.

Objective: Although surgical transmission of Creutzfeldt-Jakob disease (CJD) has been demonstrated, these iatrogenic cases account for only a small proportion of all CJD cases. The majority are sporadic CJD (sCJD) cases of unknown cause. This study investigated whether some cases classified as sCJD might have an unrecognized iatrogenic basis through surgical or other medical procedures

Methods: This study compared medical risk factors from 431 sCJD cases referred 1998 to 2006 with 454 population control subjects.