Central retinal artery occlusion (CRAO) is a rare and visually debilitating vascular condition characterized by sudden and severe vision loss. CRAO is a compelling target for intravenous alteplase (tPA) and endovascular mechanical thrombectomy (MT) due to pathophysiological similarities with acute ischemic stroke; however, the utility of these interventions in CRAO remains dubious due to limited sample sizes and potential risks. To assess usage and outcomes of tPA and MT in CRAO, we queried the National Inpatient Sample database using International Classification of Disease, Ninth and Tenth edition for patients with CRAO and acute ischemic stroke between 2010 and 2019.
View Article and Find Full Text PDFWe report the case of a 12-year-old girl with stage 4 neuroblastoma who developed tonic pupils secondary to immunotherapy with dinutuximab, an anti-GD2 antibody, based on the timeline provided by her mother with regard to onset of symptoms. The patient presented with difficulty reading and chronic dilated pupils bilaterally, according to her mother's observations over 6 months prior to presentation. Testing with dilute pilocarpine supported our presumption of tonic pupils.
View Article and Find Full Text PDFA 25-year-old man presented to an urgent care facility with sudden loss of vision in his right eye, diplopia, and anosmia. He tested positive by reverse-transcription polymerase chain reaction for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Nine days later, he presented at our emergency department, at which time ophthalmic examination revealed reduced visual acuity in the right eye, with poor color vision and a relative afferent pupillary defect.
View Article and Find Full Text PDFJ Nanosci Nanotechnol
September 2004
Amorphous nanoalloys of Co(100-x)Pt(x) (0 < or = x < or = 50) prepared sonochemically exhibit a negative magnetotransport effect, showing a maximum for platinum volume fraction of 10%. The oscillatory peak maxima observed in x = 30 composition for residual resistivity, rho0 and Tmin corresponds to the peak minima for the negative MR% in the range of compositions studied. We observe that in weakly exchange coupled amorphous alloys, the local magnetic order at Tmin and the disorder effects observed from rho0 become crucial.
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