Publications by authors named "D El Euch"
Article Synopsis
- Psoriasis is a common autoimmune skin disease, but its exact cause is still unclear; this study explores whether specific biomarkers can indicate the presence and severity of the condition.
- The research focuses on the relationship between serum levels of VEGF, MMP-9, and TIMP-2 in 115 psoriatic patients compared to 51 controls, using ELISA methods for measurement.
- Findings show that while VEGF has low effectiveness in distinguishing between psoriasis variants, the combination of TIMP-2 and inflammation Z-score significantly improves discriminative power, highlighting the role of inflammation and tissue damage in the disease's progression.
Purpose: The pathogenesis of psoriasis is characterized by a disruption of extracellular matrix (ECM) in which matrix metalloproteinases (MMPs) participate actively. We aimed to determine MMP-7 level and its association with the inflammatory response in order to determine its usefulness as a biomarker for psoriasis prediction. We also aimed to determine its distribution in uninvolved and involved psoriatic skin to evaluate the probable role of MMP-7 in psoriasis pathogenesis.
View Article and Find Full Text PDFTinea pedis and onychomycosis are among the commonest fungal diseases in the world. Dermatophytes and, less frequently, non-dermatophyte moulds are aetiological agents of foot mycosis and are capable of forming biofilms. Fungal biofilm has demonstrated increasing drug resistance.
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