Publications by authors named "D Eisele"

Objectives: Hypoglossal nerve stimulation (HGNS) is a promising surgical option for patients with obstructive sleep apnea (OSA) who are intolerant of continuous positive airway pressure therapy (CPAP). Efficacy studies for HGNS stimulation largely focus on the apnea-hypopnea index and/or oxygen desaturation index. This study's objective was to show the physiological effects of HGNS stimulation on upper airway patency, airflow, and treatment effect during polysomnography (PSG) testing.

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Objective: Health care costs are disproportionately concentrated among a small number of patients. We sought to identify variables associated with high-cost patients and high hospital concentration of high-cost patients and to examine associations with short-term outcomes in head and neck cancer (HNCA) surgery.

Study Design: The Nationwide Inpatient Sample was used to identify 170,577 patients who underwent HNCA surgery in 2001-2011.

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Translating nature's successful design principle of solution-based supramolecular self-assembling to broad applications─ranging from renewable energy and information technology to nanomedicine─requires a fundamental understanding of supramolecular hierarchical assembly. Though the forces behind self-assembly (e.g.

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Objective: This study examines the association between patient-reported allergy history and immune checkpoint inhibition (ICI) response in patients with recurrent or metastatic head and neck squamous cell carcinoma (RMHNSCC).

Study Design: Retrospective cohort study.

Setting: Academic tertiary care hospital.

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Article Synopsis
  • The study investigates how pre-existing health conditions (comorbidities) affect the response to immunotherapy in patients with advanced head and neck cancer (HNC).
  • It analyzed 93 patients, comparing outcomes for those with comorbidities versus those without, finding that patients without comorbidities had significantly better overall and progression-free survival rates and higher tumor response rates.
  • The results suggest that the presence of comorbidities is an important factor to consider when making treatment decisions for HNC patients receiving immunotherapy.
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