Helicobacter pylori regulates the expression of inhibitors of DNA binding (Id) proteins by gastric epithelial cells.

Id transcription factors control proliferation, differentiation and apoptosis by inhibiting the DNA binding of basic helix-loop-helix transcription factors. Increased expression of Id proteins promotes proliferation, inhibits differentiation, and is associated with intestinal tumorigenesis. We aimed to determine how Helicobacter pylori may alter the expression of Id proteins by gastric epithelial cells: it was hypothesised that H.

Radiological intervention in pancreatic cancer.

Pancreatic carcinoma is increasing in its incidence, and despite advances in surgical treatment and chemotherapy, its prognosis remains extremely poor. Realistic therapy is targeted primarily at the relief of obstruction of the biliary tract and the duodenum, as well as the relief of pain. This paper discusses the indications and techniques for palliation and illustrates the critical team approach between radiologist, endoscopist and surgeon.

Day-case transfer of inpatients for diagnostic and therapeutic endoscopic retrograde cholangiopancreatography.

Background: To use facilities flexibly and efficiently, a diagnostic and therapeutic endoscopic retrograde cholangiopancreatography (ERCP) service was offered to inpatients from referring hospitals on a day-case basis.

Methods: Patients were transferred by ambulance with a nurse escort and returned to the parent hospital after a short period of recovery. The activity of this service was audited.