Publications by authors named "D E Raymond"
Objective: To characterize the performance of titanium mesh (TM) (off-label) for rigid chest wall reconstruction at a single institution over a 5-year period.
Methods: Between January 1, 2019, and May 15, 2023, 22 patients (median age, 61 years) underwent chest wall resection with TM reconstruction at Cleveland Clinic. Indications for resection included sarcoma (n = 15), breast cancer (n = 2), lung cancer (n = 2), chondroblastoma (n = 1), and benign neoplasm (n = 2).
Supplemental ambient lighting intervention to improve sleep in Parkinson's disease: A pilot trial.
Parkinsonism Relat Disord
December 2024
Importance: Sleep disturbances in Parkinson's disease (PD) are common and often adversely affect quality of life. Light therapy has benefited sleep quality and mood outcomes in various populations but results to date with conventional light therapy boxes in PD patients have been mixed. We hypothesized that a passive lighting intervention, applied in the morning and designed to maximally affect the circadian system, would improve measures of sleep and mood in PD patients.
View Article and Find Full Text PDFCommentary: While examining the means, let us not neglect the ends.
J Thorac Cardiovasc Surg
September 2024
Article Synopsis
- A large-scale genome-wide association study (GWAS) was conducted with over 6000 participants to investigate genetic risk factors for isolated dystonia, aiming to improve upon earlier studies that found no significant genetic links.
- The study included 4303 dystonia patients and 2362 healthy controls, analyzing various factors like age of onset and affected body areas, but ultimately failed to identify any common genetic variants associated with dystonia.
- The findings suggest that isolated dystonia may not be influenced by common genetic variations, highlighting the need for more extensive studies like whole-genome sequencing to uncover potential genetic contributions.
Article Synopsis
- The study explores the connection between Parkinson's disease (PD) and multiple sclerosis (MS), examining cases of individuals with the G2019S genetic variant associated with both conditions.
- Out of a research cohort, 1.4% of participants had MS develop before PD, and one case showed significant brain degeneration linked to PD without typical Lewy body formation.
- The findings suggest a complex interplay between immune dysfunction and these neurodegenerative diseases, indicating that MS may occur independently and prior to PD in certain genetic carriers.