Publications by authors named "D E Pryor"
Background: Approximately half of patients with localised, high-risk soft tissue sarcoma of the extremity develop metastases. We aimed to assess whether the addition of pembrolizumab to preoperative radiotherapy and surgery would improve disease-free survival.
Methods: We completed an open-label, randomised clinical trial in patients with grade 2 or 3, stage III undifferentiated pleomorphic sarcoma or dedifferentiated or pleomorphic liposarcoma of the extremity and limb girdle.
Article Synopsis
- This observational study explores the use of x-ray images of chemoembolisation deposits for real-time image-guided radiation therapy in patients with hepatocellular carcinoma.
- The study involves 50 patients who have undergone or will undergo stereotactic ablative radiation therapy, analyzing their imaging data and developing a deep learning method for motion tracking.
- The goal is to demonstrate that the deep learning software can accurately track the placement of chemoembolisation materials, improving targeting accuracy without needing invasive procedures for fiducial markers.
Objective: To evaluate the effectiveness and safety of salvage stereotactic ablative body radiotherapy (SABR) for recurrent renal cell carcinoma (RCC) after thermal ablation (TA).
Materials And Methods: This study was a multi-institutional retrospective analysis of patients with recurrent RCC following TA who received SABR between 2016 and 2020. The primary study outcome was freedom from local failure, evaluated radiographically based on Response Evaluation Criteria in Solid Tumours (RECIST) v1.
Background And Purpose: The purpose of this study was to assess the dosimetric improvements achieved in prostate stereotactic body radiotherapy (SBRT) treatment within the PROMETHEUS and NINJA trials using an in-house real-time position monitoring system, SeedTracker.
Methods And Materials: This study considered a total of 127 prostate SBRT patients treated in the PROMETHEUS (ACTRN12615000223538) and NINJA (ACTRN12618001806257) clinical trials. The SeedTracker position monitoring system was utilized for real-time position monitoring with a 3-mm position tolerance.