Publications by authors named "D E Malone"
Marine protected areas (MPAs) are widely implemented tools for long-term ocean conservation and resource management. Assessments of MPA performance have largely focused on specific ecosystems individually and have rarely evaluated performance across multiple ecosystems either in an individual MPA or across an MPA network. We evaluated the conservation performance of 59 MPAs in California's large MPA network, which encompasses 4 primary ecosystems (surf zone, kelp forest, shallow reef, deep reef) and 4 bioregions, and identified MPA attributes that best explain performance.
View Article and Find Full Text PDFIntroduction: The population of older adults is expanding globally, but there remains a lack of healthcare professionals trained to meet growing care needs. The primary objective of this study was to compare the top three to four factors driving interest vs. lack of interest in geriatrics among pharmacy students in the United States (US) vs.
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- The study examined insecticide resistance in Anopheles gambiae sensu lato mosquitoes in coastal Côte d'Ivoire, highlighting a concern for malaria control efforts due to insufficient resistance data.
- Between 2018 and 2020, researchers analyzed mosquito populations in three health districts, finding that Anopheles coluzzii was the predominant species and demonstrating strong resistance to pyrethroids, with mortality rates below 98% even at high doses.
- Additionally, specific genetic mutations related to resistance were identified, revealing high prevalence of kdr 995F and varying frequencies of Ace-1 280S, indicating a complex resistance profile that emphasizes the need for updated vector control strategies.
Article Synopsis
- Type 2 diabetes (T2D) is a significant health issue in the U.S., and this study focuses on how racial and ethnic differences affect the prescription of effective diabetes medications.
- The research analyzed data from 57,320 patients, revealing notable disparities in the prescription rates of GLP-1 medications like tirzepatide, semaglutide, and dulaglutide among different racial and ethnic groups compared to White patients.
- The findings suggest that these disparities could lead to worse health outcomes for underrepresented groups, signaling a need for targeted interventions to ensure equitable access to diabetes care.
Article Synopsis
- AJHP is publishing accepted manuscripts online quickly, but these versions aren't the final formatted ones; they will be updated later after author proofing.
- The PANAMO study tested vilobelimab, which helps reduce inflammation in severe COVID-19 patients on mechanical ventilation, showing a significant reduction in mortality over 28 and 60 days.
- A cost-effectiveness analysis revealed that adding vilobelimab to standard care resulted in higher costs ($132,247 vs. $103,414) but also provided more quality-adjusted life-years (7.99 vs. 6.70 QALYs), with an incremental cost-effectiveness ratio of $22,287/QALY.