Publications by authors named "D E Maier"

Objective: The pathophysiological mechanisms of dysphagia in individuals with traumatic cervical spinal cord injury (SCI) are not well understood yet. Several risk factors for developing dysphagia after SCI were postulated including mechanical ventilation, tracheostomy, age, female sex, anterior surgical approach, SCI severity, and multi-level spinal fusion. This study aimed to identify risk factors for dysphagia in individuals who sustained traumatic cervical SCI.

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Background: Spinal cord injury results in permanent neurological impairment and disability due to the absence of spontaneous regeneration. NG101, a recombinant human antibody, neutralises the neurite growth-inhibiting protein Nogo-A, promoting neural repair and motor recovery in animal models of spinal cord injury. We aimed to evaluate the efficacy of intrathecal NG101 on recovery in patients with acute cervical traumatic spinal cord injury.

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Aflatoxins (AF), fungal metabolites, can contaminate feed in favorable environments, posing health risks to humans and animals. Dairy cows exposed to aflatoxin B1 (AFB1) excrete its metabolite, aflatoxin M1 (AFM1), in milk, compromising its safety. The current study examined the use of an AF binder in dairy feed concentrates on farms in Rwanda to mitigate AFM1 in milk.

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Magnetic resonance imaging (MRI) remains the gold standard for evaluating spinal cord tissue damage after spinal cord injury (SCI). Several MRI findings may have some prognostic potential, but their evolution over time, especially from the subacute to the chronic phase has not been studied extensively. We performed a prospective observational longitudinal study exploring the evolution of MRI parameters from the subacute to chronic phase after human traumatic cervical SCI.

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