Duration of Mydriasis Produced by 0.5% and 1% Tropicamide in Sprague-Dawley Rats.

Ophthalmic examination (OE) is a common part of preclinical studies. Pupillary dilation to facilitate OE may affect results of other planned testing. The purpose of this study was to determine the duration of mydriasis produced by commercially available 0.

Parental failure in captive cotton-top tamarins (Saguinus Oedipus).

Several New World monkey species experience high rates of infant mortality in captivity, and parental failure in the form of infant neglect and abuse is often regarded as one of the leading causes of this problem. We explored a large archival database to assess environmental, familial, and biological variables identified as significant for parental success in previous studies of captive tamarins, through several generations and across several dozen pedigrees. Using a stepwise multiple regression analysis we developed a model including the fewest variables able to identify statistically significant predictors of infant outcome.

Anaesthetic management of baboons undergoing heterotopic porcine cardiac xenotransplantation.

A detailed anaesthetic technique for baboons (Papio anubis) undergoing heterotopic abdominal cardiac xenotransplantation is described. Twenty-two baboons served as transplant recipients. Donors were either crossbred farm pigs (Sus scrofa) (n = 4) or transgenic pigs (Sus scroefa) (n = 18) expressing human complement regulatory proteins on the endothelium.