Publications by authors named "D E Laban"
Article Synopsis
- Adult medulloblastoma is uncommon, and treatment insights are mostly drawn from studies of pediatric cases; this study analyzed adult cases treated at King Hussein Cancer Center to understand clinical features and outcomes.
- The study included 53 patients aged 18 and older, with comprehensive assessments of disease characteristics and treatment responses over a median follow-up of 70 months, noting that 37.7% of patients died during this period.
- The findings highlighted significant correlations between patient outcomes and factors such as the extent of surgery and risk status, while molecular subgrouping did not predict survival outcomes, indicating a need for more aggressive treatment in high-risk patients.
Introduction: Most pediatric low-grade-gliomas (LGG) and some high-grade-gliomas (HGG) have alterations in the RAS/MAPK pathway. Promising high tumor response rates were achieved using BRAF/MEK inhibitors, however data on their use in low-middle-income-countries (LMICs) are limited.
Methods: We retrospectively reviewed our Jordanian experience of using compassionate BRAF/MEK inhibitors in treating children with gliomas.
The occurrence of primary fourth ventricular lymphoma is an exceptionally uncommon phenomenon. Here, we present a case of lymphoma in the fourth ventricle in a 30-year-old male who presented with progressive headache and vertigo over the last one month of his presentation. Preoperative MRI revealed a space-occupying lesion of the fourth ventricle.
View Article and Find Full Text PDFBackground: Breast cancer remains a leading cause of cancer-related mortality and morbidity worldwide. Ocular and periocular metastasis present as a rare but clinically significant manifestation. This study aims to explore demographics and clinical aspects of ocular and periocular metastasis in breast cancer patients.
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