[Modifying action of Mn(II) chelate with ethyl ester of salicylydene tyrosine on some biophysical parameters of erythrocyte membranes of the irradiated organism].

The presentation summarizes the results of studies on radioprotective activity of newly synthesized Mn(II) chelate with ethyl ester of salicylydene D,L-tyrosine, basing on the evaluation of its membrane-protective effects, revealed at different periods post the exposure of the organism to ionizing radiation. It was revealed that the administration of the compound into the animal organism before the radiation exposure (gamma-irradiation of 60Co at a dose level of 4.8 Gy) produced correcting action on structure-functional properties of erythrocyte membrane of irradiated rats: the excessive activation of lipid peroxidation of erythrocyte membranes was inhibited, the passive permeability of erythrocytes for K+ ions was normalized, the deformity and membrane potential of erythrocytes according to hydrogen-chlorine gradient were recovered.

[Electromagnetic fields of millimeter range: effect on the structure and functional properties of erythrocyte membranes].

The effect of coherent and non-coherent electromagnetic fields of millimetre range on biophysical and biochemical indices of blood erythrocytes and plasma of the animals totally exposed to radiation at various periods of observation (day 1, 5, 10) was studied. The following structure-functional shifts were revealed: deviations in the content of separate phospholipid fractions of erythrocyte membranes, the changes of lipid peroxidation products in erythrocyte membranes and blood plasma of the irradiated animals, statistically significant increase of K ions out-flow from the erythrocytes, as well as the alteration of the value of membrane potential of erythrocytes.

[Changes in the parameters of the rhythms of the electrolyte-excreting function of the kidneys in women in relation to the seasons of the year].

The characteristics (period, mesor, amplitude) of the rhythms of urinary excretion of sodium, potassium, chlorine, calcium, magnesium, and phosphorus were examined in normal women during various seasons. The urine was collected for 5 days with 4-hour intervals. The rhythms were detected and their parameters established with the use of mathematical methods for the assessment of the tested curve fragments repetitions and by the least squares nonlinear method.

[Rhythms of electrolyte excretion in healthy people].

The rhythms of urinary electrolyte excretion have been examined in normal subjects by following up every examinee for 72-120 hrs. Circadian rhythms have been detected in the predominant majority of the examinees. The mean values of other rhythm parameters (mesor, amplitude) have been established, that are suggested to be used as the reference values in the early diagnosis of abnormalities, with due consideration for the ecologic conditions and nutrition.