SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire.

During thymic development, most γδ T cells acquire innate-like characteristics that are critical for their function in tumor surveillance, infectious disease, and tissue repair. The mechanisms, however, that regulate γδ T cell developmental programming remain unclear. Recently, we demonstrated that the SLAM/SAP signaling pathway regulates the development and function of multiple innate-like γδ T cell subsets.

Aging increases lightness of grass-fed beef.

Grass-fed beef is becoming increasingly popular and is expected to be a $14 billion industry by 2024. Even so, grass-fed beef is typically darker in appearance than that of conventional grain-fed beef. Aging has been shown to improve lean color (*, *) of dark-cutting beef however little work has focused on aging as it relates to improving the lean color of grass-fed beef.

In vitro proteolysis mirrors intact muscle maturation in beef carcasses.

An in vitro assay was developed to study protease activity during the maturation of beef postmortem. Myofibrils were purified from the semitendinosus and used as a sentinel for assessing the activity of endogenous proteases in longissimus thoracis et lumborum (LTL) and the extensor carpi radialis (ER) over time postmortem in beef carcasses. Samples were collected from each muscle at 0, 1, 2, 7, and 14 d of aging and snap frozen.

The Rate of Water Safety Team Interventions in High Diving, A Survey of Elite Athletes Performing between 2009 and 2021.

There is a paucity of sport-specific safety data on high diving. This paper describes the results of a survey of all athletes competing in elite international competitions between 2009 and 2021.Sixty-eight athletes completed surveys, representing a response rate of 80%.

Mitochondrial Abundance and Function Differ Across Muscle Within Species.

: Mitochondria are considered the powerhouse of cells, and skeletal muscle cells are no exception. However, information regarding muscle mitochondria from different species is limited. : Different muscles from cattle, pigs and chickens were analyzed for mitochondrial DNA (mtDNA), protein and oxygen consumption.