Publications by authors named "D E E Rizk"

Objectives: Out-of-hospital cardiac arrest (OHCA) victims receiving defibrillation from an automated external defibrillator (AED) placed early in the chain of survival are more likely to survive. We sought to explore the accuracy of AED pad placement for lay rescuers (LR) and first responders (FR).

Methods: We conducted a secondary analysis of data collected during randomized OHCA simulation trials involving LRs and FRs.

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Article Synopsis
  • Enterohemorrhagic Escherichia coli (EHEC) O157 is known for causing serious illnesses like hemorrhagic colitis and hemolytic uremic syndrome, but non-O157 strains are also emerging as significant pathogens.
  • In a study conducted in Egypt, 335 samples were collected, revealing that nearly half were EHEC, with the O111, O91, O26, and O55 serotypes being the most common across various sources like stool, urine, and food products.
  • The analysis of virulence genes showed high prevalence of genes such as sheA, stx2, and eae, and genetic testing revealed diverse strains with significant similarities, highlighting the complexity and potential
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Background: The alternative complement pathway plays a key role in the pathogenesis of IgA nephropathy. Iptacopan specifically binds to factor B and inhibits the alternative pathway.

Methods: In this phase 3, double-blind, randomized, placebo-controlled trial, we enrolled adults with biopsy-confirmed IgA nephropathy and proteinuria (defined as a 24-hour urinary protein-to-creatinine ratio of ≥1 [with protein and creatinine both measured in grams]) despite optimized supportive therapy.

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Background Gestational diabetes mellitus (GDM) can be defined as hyperglycemia that develops during pregnancy. GDM poses both maternal and fetal potential risks. Elevated maternal cortisol levels have been linked to maternal hyperglycemia and insulin resistance.

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