Publications by authors named "D E Drachenberg"

Article Synopsis
  • Patients undergoing open radical cystectomy have a high risk of needing blood transfusions, and the study investigates the use of tranexamic acid (TXA) to potentially reduce this risk.
  • The TACT trial was a randomized, double-blind study conducted in 10 academic centers from 2013 to 2021, involving patients scheduled for this type of surgery due to bladder cancer.
  • Results showed no significant difference in RBC transfusion rates between the TXA group and the placebo group, with both groups needing transfusions at similar rates up to 30 days post-surgery.
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Article Synopsis
  • * A survey conducted among 38 investigators at 22 sites revealed that while most recognize the importance of genetic testing in advanced cases, access issues and uncertainties hinder broader implementation.
  • * The researchers recommend developing an algorithm to guide healthcare providers in determining when and how to perform genetic testing for prostate cancer patients, aiming to improve access and clarity in testing practices.
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Purpose: To compare characteristics and outcomes of patients included versus those not in adjuvant therapy trials post complete resection of renal cell carcinoma (RCC).

Methods: Adult patients following complete resection for clear cell RCC between January 1, 2011, and March 31, 2021, were included. Patients had intermediate high, high risk nonmetastatic disease (modified UCLA Integrated Staging System) or fully resected metastatic (M1) disease as per the inclusion criteria of adjuvant studies.

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Purpose: There are conflicting reports regarding radical cystectomy complication risk from obesity subcategories, and a BMI threshold below which complication risk is notably reduced is undefined. A BMI threshold may be helpful in prehabilitation to aid patient counseling and inform weight loss strategies to potentially mitigate obesity-associated complication risk. This study aims to identify such a threshold and further investigate the association between BMI subcategories and perioperative complications from radical cystectomy.

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Purpose: Treatment selection for localized prostate cancer is guided by risk stratification and patient preferences. While socioeconomic status (SES) disparities exist for access to care, less is known about the effect of SES on treatment decision-making. We sought to evaluate whether income status was associated with the treatment selected (radical prostatectomy [RP] vs radiation therapy [RT]) for nonmetastatic prostate cancer in a universal health care system.

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