Publications by authors named "D Dubois"

Introduction: To date, surveillance of vaping among Canadians (using vaping products with or without nicotine) has largely been examined with respect to age and smoking status. However, a nationally representative examination of a broad set of characteristics is lacking. This study characterized Canadians aged 15 years and older who vape, stratified by smoking status.

View Article and Find Full Text PDF
Article Synopsis
  • TROP2 is a promising target for antibody-drug conjugates in treating aggressive breast cancers, but its role as a predictive marker remains unclear.
  • Researchers compared different methods for assessing TROP2 levels in breast cancer tissues to establish reliable evaluation criteria.
  • Findings suggest using HER2 IHC guidelines for TROP2 assessment is effective and may lead to better predictions of treatment responses in future studies.
View Article and Find Full Text PDF

Metal chalcogenide nanoparticles have been attracting extensive attention in diverse fields. Traditionally these nanoparticles are stabilized by organic ligands such as thiols and amines involving nonconjugated core-ligand interfacial interactions. In the present study, a facile wet-chemistry method is described for the synthesis of palladium disulfide (PdS) nanoparticles capped with acetylene derivatives.

View Article and Find Full Text PDF

Unspecific bone uptake (UBU) related to [F]PSMA-1007 PET/CT imaging represents a clinical challenge. We aimed to assess whether a combination of clinical, biochemical, and imaging parameters could predict skeletal metastases in patients with [F]PSMA-1007 bone focal uptake, aiding in result interpretation. We retrospectively analyzed [F]PSMA-1007 PET/CT performed in hormone-sensitive prostate cancer (PCa) patients at 3 tertiary-level cancer centers.

View Article and Find Full Text PDF

Objectives: Performance evaluation of routine laboratory methods to determine the susceptibility of Enterobacterales urinary isolates to fosfomycin (oral administration) and mecillinam.

Methods: We collected 347 Enterobacterales isolates from monomicrobial midstream urine samples from women with significant bacteriuria and leukocyturia. Mostly non-Escherichia coli isolates (i.

View Article and Find Full Text PDF