Publications by authors named "D Dockrell"
Background: Live attenuated influenza vaccines (LAIVs) alter nasopharyngeal microbiota in adults. It is poorly understood why LAIV immunogenicity varies across populations, but it could be linked to the microbiome. We aimed to investigate the interactions between intranasal immunisation with LAIV and nasopharyngeal microbiota composition in children from The Gambia.
View Article and Find Full Text PDFSmoking is one of the major contributors to airway injuries. N-acetylcysteine (NAC) has been proposed as a treatment or preventive measure for such injuries. However, the exact nature of the smoking-induced injury and the protective mechanism of NAC are not yet fully understood.
View Article and Find Full Text PDFArticle Synopsis
- Pain is a significant issue for individuals with inflammatory arthritis (IA), affecting their overall well-being, and current UK pain management often relies on long-term opioids and gabapentinoids without sufficient evidence for their effectiveness.
- Surveys indicate that non-drug therapies for pain relief are not being utilized as much as they could be, highlighting a gap in treatment options.
- The British Society for Rheumatology is creating a new guideline to provide clear, evidence-based recommendations for pain management in IA, aimed at healthcare professionals, patients, and other stakeholders, ensuring comprehensive care for people living with this condition.
Article Synopsis
- Paget's disease of bone (PDB) makes bones grow and change shape in a messy way, which can lead to problems like pain, deafness, and broken bones.
- A study with 168 people found that about 73% of them had musculoskeletal pain, mainly because of osteoarthritis in joints away from the PDB affected areas.
- The research showed that pain was more common in older folks and women, and highlighted the need to check each person's pain to treat it correctly.