Publications by authors named "D Dive"

The number of ageing people with relapsing multiple sclerosis (RMS) is increasing. The efficacy of disease-modifying therapies (DMTs) for RMS declines with age. Also, older persons with MS may be more susceptible to infections, hospitalisations and malignancy.

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Access to, standardization and reimbursement of multidisciplinary care for people with MS (PwMS) is lacking in many countries. Therefore, this study aims to describe the current multidisciplinary care for people with MS (PwMS) in Belgium and identify benefits, needs and future perspectives METHODS: A survey for PwMS questioned various aspects of MS and viewpoints on care. For MS nurses (MSN) and neurologists, employment, education, job-content, care organization and perspectives were inquired.

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Article Synopsis
  • A study investigated the use of brain age, calculated through neuroimaging, as a communication tool for assessing brain health in multiple sclerosis (MS) patients.
  • The researchers used a linear regression model to predict brain age and tested its relationship with cognitive performance, specifically through the Symbol Digit Modalities Test (SDMT).
  • Results showed a significant correlation between brain age and cognitive scores in MS patients, suggesting that brain age could serve as a useful biomarker for cognitive dysfunction in MS.
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Multiple sclerosis is a central nervous system autoimmune disease of the white and grey matters. Its pathophysiology is much better well known. It results from the interaction between genetic and environmental susceptibility factors.

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Atezolizumab successfully reinvigorated JC virus immunity in a patient in Belgium with progressive multifocal leukoencephalopathy, as demonstrated by clinical, virologic, and radiologic response to treatment. However, the treatment also resulted in immune reconstitution inflammatory syndrome and life-threatening immune-related adverse events. These conditions were treated with corticosteroids, leading to treatment resistance.

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