Publications by authors named "D Di Noia"

Accumulating data suggest that matrix metalloproteinases (MMPs), in particular MMP-2 and MMP-9, are deleterious after acute ischaemic stroke. A beneficial effect of MMPs in the repairing phases of cerebral ischaemia has also been proposed. This study investigated the relationship between MMP-2 and MMP-9 and stroke subtypes, clinical recovery and haemorrhagic transformation (HT).

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Dysfunction of the baroreceptor structures located in the carotid bulb is considered responsible for hypotensive responses to orthostatic posture in hypertensive subjects. Because of a recurrent vascular impairment in essential hypertensives, the authors hypothesized that in these cases the baroreceptive dysfunction could be related to some peculiar vascular disarrangement of the carotid arteries, at the level of the bulb. To test this, they compared two groups of mild essential hypertensives, divided into group A--15 subjects considered hyporeacting because of a decrease in mean blood pressure > or = 10 mmHg at the first minute of a passive orthostatic stress--and group B--15 subjects considered normoreacting because of an increase in mean blood pressure > or = 5 mmHg.

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The aim of this study was to evaluate the effect of lacidipine and nifedipine on lower limb veins. Forty hypertensive patients, aged 30-50 years, with no deep venous thrombosis, venous insufficiency, or hypothyroidism underwent double-blind treatment with placebo (1 week), lacidipine 4 mg once daily (1 week), and slow-release nifedipine 20 mg twice daily (1 week) in randomized sequence. Echo-color Doppler examination of superficial, deep, communicating, and perforating veins of the legs was performed.

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