Publications by authors named "D Dewailly"

Article Synopsis
  • * The article aims to examine how the presence of PCOM affects the diagnosis, treatment, and long-term implications for women with functional hypothalamic amenorrhoea (FHA), indicating that those with FHA and PCOM may have different endocrine and metabolic traits.
  • * Research shows that the prevalence of PCOM in women with FHA ranges from 41.9% to 46.7%, indicating a higher rate compared to those without PCOS, which could be
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Objective: To compare the ongoing pregnancy rate per initiated cycle between patients with functional hypothalamic amenorrhea (FHA) and patients with congenital hypogonadotropic hypogonadism (CHH) treated with pulsatile gonadotropin-releasing hormone (GnRH) administration.

Design: Retrospective monocentric cohort study conducted at the University Hospital of Lille from 2004 to 2022.

Setting: Lille University Hospital, Department of Endocrine Gynecology.

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Article Synopsis
  • In a study of women referred for potential PCOS, it was found that at least 2% were misdiagnosed and actually had Functional Hypothalamic Amenorrhea (FHA).
  • There is a need for better diagnostic markers to distinguish between PCOS and FHA to prevent misdiagnosis.
  • Incorrect treatment for undiagnosed FHA could lead to harmful long-term effects for women.
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Background: In functional hypothalamic amenorrhea (FHA), luteinizing hormone and follicle-stimulating hormone levels show high interindividual variability, which significantly limits their diagnostic value in differentiating FHA from polycystic ovary syndrome (PCOS). Our aim was to profile the LH:FSH ratio in a large sample of patients with well-defined FHA.

Methods: This observational study included all consecutive patients with FHA presenting to the Department of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Vienna, between January 2017 and August 2023.

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Background: d-Chiro-inositol is a natural molecule that, in association with its well-studied isomer myo-inositol, may play a role in treating various metabolic and gynecological disorders.

Objectives: This perspective seeks to explore the mechanisms and functions of d-chiro-inositol, laying the foundations to discuss its use in clinical practice, across dysmetabolism, obesity, and hormonal dysregulation.

Methods: A narrative review of all the relevant papers known to the authors was conducted.

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