Fetal toxoplasmosis: outcome of pregnancy and infant follow-up after in utero treatment.

Eight-nine cases of fetal Toxoplasma infection are reported in women treated with spiramycin during pregnancy. Thirty-four pregnancy terminations were performed (2.7% of the total number of acquired Toxoplasma infections during pregnancy).

Physiology and management of intrauterine growth retardation: a biologic approach with fetal blood sampling.

Intrauterine growth retardation is a major contributor to perinatal mortality and morbidity. The most important obstetric problem is to determine which fetuses are well in utero and which are at risk of irreversible damage or severe and prolonged neonatal morbidity. The optimal timing of delivery is at present made by subjective assessment of clinical variables.

Assessment of fetal blood volume for computer-assisted management of in utero transfusion.

We performed 41 intravascular ultrasound-guided fetal transfusions in a total of 20 pregnancies with erythroblastosis fetalis or alloimmune thrombocytopenia. On the basis of this experience, we developed a computer-assisted procedure for determining the volume to be transfused, which provides an adequate final concentration. Fetal weight was estimated using ultrasound measurements.