Publications by authors named "D Della Morte"
Actinic keratosis (AK) is a precursor to invasive squamous cell carcinoma, making early diagnosis and treatment essential to prevent progression. Among available therapeutic options, nicotinamide (NAM) has shown potential in reducing AK progression. NAM is a precursor of nicotinamide adenine dinucleotide (NAD), which activates sirtuin (SIRT)1, a protein with anti-cancer properties.
View Article and Find Full Text PDFFar-Infrared Radiation (FIR) is emerging as a novel non-invasive tool for mitigating inflammation and oxidative stress, offering potential benefits for certain medical conditions such as cardiovascular disease and chronic inflammatory disorders. We previously demonstrated that the application of patch-based FIR therapy on human umbilical vein endothelial cells (HUVECs) reduced the expression of inflammatory biomarkers and the levels of reactive oxygen species (ROS). Several in vitro studies have shown the inhibitory effects of FIR therapy on cell growth in different cancer cells (including murine melanoma cells), mainly using the wound healing assay, without direct cell motility or tracking analysis.
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- The study explored how common sleep problems are among older adults, focusing on differences between men and women as well as different age groups.
- It included 58 participants, with major complaints being poor sleep quality (36.2%), sleep apnea risk (34.5%), and insomnia symptoms (25.9%), with older women experiencing worse sleep issues than men.
- The findings suggest that sleep problems are prevalent in older adults, highlighting the need for screening and treatment to help improve their overall well-being and lessen related health issues.
Article Synopsis
- Leukocytoclastic vasculitis (LCV) is a type of inflammation affecting small blood vessels, primarily in the skin, with several possible causes, including autoimmune conditions, infections, and sometimes occurs without a known cause.
- A case report details a 73-year-old man who developed skin-limited LCV after starting weekly injections of semaglutide, a medication for type 2 diabetes, which resolved quickly after stopping the drug.
- The conclusion highlights the need for further research and monitoring to determine how common LCV might be as a side effect of both oral and injectable forms of semaglutide.
Currently, exposome studies include a raft of different monitoring tools, including remote sensors, smartphones, omics analyses, distributed lag models, etc. The similarity in structure between the exposome and the microbiota plus their functions led us to pose three pertinent questions from this viewpoint, looking at the actual relationship between the exposome and the microbiota. In terms of the exposome, a bistable equilibrium between health and disease depends on constantly dealing with an ever-changing totality of exposures that together shape an individual from conception to death.
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