Publications by authors named "D DeFigueiredo"

Objective: To determine the need for fetal karyotyping in cases of an isolated single umbilical artery (SUA) identified during the second-trimester routine anomaly scan.

Methods: All patients booked for antenatal care and delivery in our hospital are offered two ultrasound scans in pregnancy, one at 11-13 weeks' gestation as part of screening for chromosomal defects and another at 20-23 weeks for detailed fetal examination. In addition we examine patients referred from other hospitals because of suspected fetal abnormalities during their routine second-trimester scan.

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Objective: To examine the association between single umbilical artery (SUA) and cardiac defects and to determine whether patients with SUA require specialist fetal echocardiography.

Methods: Incidence and type of cardiac defects were determined in fetuses with SUA detected at routine second-trimester ultrasound examination.

Results: A routine second-trimester scan was performed in 46 272 singleton pregnancies at a median gestation of 22 (range, 18-25) weeks and an SUA was diagnosed in 246 (0.

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Objective: To determine the value of measuring fetal femur and humerus length at 11-14 weeks of gestation in screening for chromosomal defects.

Methods: Femur and humerus lengths were measured using transabdominal ultrasound in 1018 fetuses immediately before chorionic villus sampling for karyotyping at 11-14 weeks of gestation. In the group of chromosomally normal fetuses, regression analysis was used to determine the association between long bone length and crown-rump length (CRL).

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Objective: To analyse patient data to elucidate the apparent association between an abnormal karyotype and tricuspid regurgitation found during fetal echocardiography at early gestations.

Setting: Tertiary referral centre for fetal medicine and cardiology.

Methods: Fetuses between 11 and 14 weeks' gestation were selected for detailed echocardiography.

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