Publications by authors named "D De Giorgio"

: Oral cavity squamous-cell carcinoma is among the most frequent head and neck neoplasms. Early-stage T1/T2N0 accounts for 40/45% of new diagnoses. Of these, about 30% of cases hide occult metastases in the neck.

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Article Synopsis
  • CRALE (Cardiopulmonary resuscitation-associated lung edema) is a condition observed in patients who undergo cardiac arrest and CPR, influencing both respiratory and cardiovascular systems.
  • An experimental model of cardiac arrest was used to study CRALE, with manual and mechanical chest compressions compared, showing significant respiratory complications due to decreased lung compliance and poor oxygen delivery.
  • Results indicated that after 25 minutes of CPR, animals exhibited signs of CRALE such as increased lung weight and reduced aeration, suggesting a correlation between CPR mechanics and lung edema severity.
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Microsurgery is the gold standard for hard and soft tissue reconstruction in head and neck neoplasia and malformations. Fibular, iliac crest, and scapular free flaps are the main choices for reconstructive surgery of the jaws. Although widely described in the literature, no statistical comparison analysis of the donor site morbidity of these has been performed to our knowledge.

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Purpose: To report a case of macular hole and detachment occurring after the subretinal injection of Voretigene Neparvovec (VN) in a patient affected by atypical RPE65 retinal dystrophy with high myopia and its successful surgical management.

Case Description: We report a case of a 70-year-old man treated with VN in both eyes. The best corrected visual acuity (BCVA) was 0.

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