Publications by authors named "D Dawes"
MEN2 phenotype in a family with germline heterozygous rare RET K666N variant.
Endocrinol Diabetes Metab Case Rep
July 2024
Article Synopsis
- MEN2 is a hereditary cancer syndrome linked to mutations in the RET proto-oncogene, with MEN2A being the most common form, involving risks for medullary thyroid cancer, pheochromocytoma, and primary hyperparathyroidism.
- The specific RET variant K666N is rare, and most associated patients generally present with a mild form of medullary thyroid cancer; however, one case showed more severe symptoms including pheochromocytoma.
- A reported case involves a young proband who developed severe complications post-surgery, revealing a RET K666N variant alongside pheochromocytoma, medullary thyroid cancer, and primary hyperparathyroidism, indicating it may have low penetrance in MEN
Background: Conducted electrical weapons (CEWs) are nonlethal weapons used in tactical environments. Tactical EMS (TEMS) operators provide patient care in environments where CEWs are present. CEWs may produce a spark that can be a source of ignition.
View Article and Find Full Text PDFObjective: Some scholars have criticized pretrial assessments for perpetuating racial bias in the criminal legal system by offering biased predictions of future legal system outcomes. Although these critiques have some empirical support, the scholarship has yet to examine the predictive validity and differential prediction of pretrial assessments across individuals by their age. Following the guidance of the life-course literature, the present study serves as the first age-graded evaluation of the Public Safety Assessment (PSA) focused on assessing whether the predictive validity and scoring predictions of the tool vary across the lifespan.
View Article and Find Full Text PDFArticle Synopsis
- The objective of the study was to assess how accessible scientific literature is for providers in cancer genomics, as they need this information for patient care concerning tumor genome alterations.
- Researchers analyzed 265 journals based on their accessibility while evaluating clinical test results for 1,842 cancer patients, finding that nearly half of the journals had open access within a year.
- The study concluded that while universities generally provided good access to subscription journals, access from hospital systems was inconsistent, highlighting challenges in the availability of scientific literature as genomic medicine advances.