Publications by authors named "D Dasgupta"
Objectives: Computer-assisted planning (CAP) allows faster SEEG planning and improves grey matter sampling, orthogonal drilling angles to the skull, reduces risk scores and minimises intracerebral electrode length. Incorporating prior SEEG trajectories enhances CAP planning, refining output with centre-specific practices. This study significantly expands on the previous work, compares priors libraries between two centres, and describes differences between SEEG in adults and children in these centres.
View Article and Find Full Text PDFBackground: Optimal dosing of rituximab when given with mycophenolate mofetil (MMF) for frequently relapsing nephrotic syndrome/steroid-dependent nephrotic syndrome (FRNS/SDNS) remains uncertain.
Methods: This was a prospective, non-inferiority, open-label randomized controlled multicentre study. Children (2-18 years old) with difficult FRNS/SDNS were randomized to group A (rituximab 375 mg/m once) or group B (rituximab 375 mg/m twice; 7-14 days apart) followed by continuous MMF and 3 months of tapered steroids.
Unveiling the chromate stress response in the marine bacterium Bacillus enclensis AGM_Cr8: a multifaceted investigation.
World J Microbiol Biotechnol
November 2024
Article Synopsis
- - The study introduces Bacillus enclensis AGM_Cr8, a marine bacterium found in polluted Versova Creek, Mumbai, that displays significant tolerance to chromate stress and other heavy metals such as lead and arsenic.
- - Various microscopic techniques show how AGM_Cr8 absorbs chromate, with evidence of both surface interaction and internal bioaccumulation, suggesting a bioreduction mechanism that converts harmful Cr(VI) into less toxic Cr(III).
- - Genome sequencing reveals twenty-two genes related to chromate tolerance and detoxification processes, indicating AGM_Cr8's potential for bioremediation of chromium contamination in the environment.
Article Synopsis
- - Cadmium (Cd) is a toxic heavy metal that can harm health through inhalation, smoking, or contaminated food, and is linked to chronic lung diseases like COPD and pulmonary fibrosis.
- - A study on C57BL/6 mice showed that exposure to cadmium chloride led to inflammation, increased lung resistance, and changes in immune cell populations, particularly a decrease in CD4 T-cells and an increase in CD8 T-cells.
- - The research highlights the need for more studies to understand how cadmium causes lung damage and immune system disruption, which is vital for finding treatments for lung diseases related to cadmium exposure.
Article Synopsis
- The study evaluates the long-term outcomes of lens-sparing vitrectomy (LSV) in 23 eyes of patients with stage 4 retinopathy of prematurity (ROP) after an average follow-up of over 7 years.
- Results show that 69.57% of lenses remained clear, 82.61% of eyes had an attached retina, and 34.78% achieved good vision (≥6/24).
- While some patients experienced severe myopia, the majority retained functional vision, with 68.75% showing visual capability in at least one eye despite complications like retinal detachments.