Publications by authors named "D Daniel Hunt"
Fever in the Trauma Bay: A Marker for Greater Risk of Adverse Outcomes.
Surg Infect (Larchmt)
January 2025
Previous work identified a sub-group of trauma patients at risk for bacteremia who presented with signs of infection, including fever. A majority were older adult falls who had early onset bacteremia. Fever in the trauma bay is associated with a greater risk of adverse outcomes and identifies patients who might benefit from early initiation of interventions for sepsis.
View Article and Find Full Text PDFJYNNEOS, a third-generation smallpox vaccine, is integral to monkeypox virus (MPXV) control efforts, but the durability of this modified vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine's effectiveness is undefined. We optimized and used a plaque reduction neutralization test (PRNT) with authentic clade IIa MPXV and vaccinia virus to assess antibody responses over 12 months in 8 donors vaccinated with 2 doses of JYNNEOS. One donor previously received the ACAM2000 vaccine; 7 donors were smallpox vaccine-naive.
View Article and Find Full Text PDFArticle Synopsis
- The TAOK proteins are important kinases involved in various cellular functions and are linked to neurodevelopmental disorders (NDDs) like those caused by TAOK1 and TAOK2 variants.
- A study analyzed clinical and genetic data from individuals with these variants, revealing that TAOK1 variants lead to significant neurodevelopmental issues and some novel characteristics, while TAOK2 variants are tied to neurodevelopmental abnormalities, autism, and obesity.
- This research expands the understanding of these disorders by presenting the largest cohort of individuals with TAOK1-NDD and identifying new variants and phenotypes associated with both TAOK1 and TAOK2.
Article Synopsis
- The LUX-ZEPLIN (LZ) experiment is a significant scientific study using a dual-phase xenon chamber located underground in South Dakota to search for dark matter interactions.
- The study extends existing theories to include relativistic effects, providing new constraints on the interactions between weakly interacting massive particles and nucleons based on their electric and magnetic dipole moments.
- Results include 90% confidence level limits on the coupling strength of five different interactions, analyzed over a specific energy range, which advances our understanding in particle physics beyond previous nonrelativistic effective field theories.
Article Synopsis
- A study aimed to explore the links between running biomechanics and the musculotendinous characteristics of adolescent runners, as well as changes in these properties over a period of six months.
- Thirty-three adolescents participated, undergoing ultrasound evaluations and wearable sensor assessments to analyze different muscle and tendon attributes and running mechanics.
- Results showed that specific biomechanics, like pronation and contact time, significantly predicted changes in muscle and tendon thickness, highlighting potential influences of running mechanics on physical development in young athletes.