: This case study investigates the effect of a five-session whole-body cryostimulation (WBC) cycle on a 55-year-old female patient with cerebral palsy (CP) and lower limb spasticity (LLS) with a typical diplegic gait pattern. CP is a common physical disability characterized by motor impairments, including spasticity, which significantly impacts mobility and quality of life. The current treatments for spasticity often have limited efficacy and considerable side effects, making alternative therapies like WBC an area of interest.
View Article and Find Full Text PDFThis study compares the workability, mechanical, and thermal characteristics of structural self-compacting lightweight concrete (SCLWC) formulations using pumice aggregate (PA), expanded perlite aggregate (EPA), fly ash (FA), and silica fume (SF). FA and SF were used as partial substitutes for cement at a 10% ratio in various mixes, impacting different aspects: According to the obtained results, FA enhanced the workability but SF reduced it, while SF improved the compressive and splitting tensile strengths more than FA. EPA, used as a fine aggregate alongside PA, decreased the workability, compressive strength, and splitting tensile strength compared to the control mix (K0).
View Article and Find Full Text PDFWe have previously experimentally observed high-power Stokes and second-order Stokes output from a mm-sized CaF disk using stimulated Raman scattering. A pump laser at a wavelength of 1.06 µm was coupled via a tapered fiber to the whispering gallery modes (WGM) of the disk.
View Article and Find Full Text PDFObjective: This study evaluated short- and long-term efficacy and safety of the second-generation somatostatin receptor ligand pasireotide alone or in combination with dopamine agonist cabergoline in patients with Cushing's disease (CD).
Study Design: This is an open-label, multicenter, non-comparative, Phase II study comprising 35-week core phase and an optional extension phase. All patients started with pasireotide, and cabergoline was added if cortisol remained elevated.