Ultra-processed foods and the strategic manipulation of our evolved motivational tendencies.

Background: Consumption of ultra-processed foods (UPFs) is responsible for an increasing proportion of non-communicable diseases and premature mortality. Recognition of the commercial and social determinants of UPF consumption represents an important advance in public health, with implications for interventions that emphasize regulatory policies rather than individual motivation. However, it is important not to lose sight of the motivational mechanisms through which commercial and social determinants exert their effects on unhealthy behavior.

Adverse drug reactions and events in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: the development and validation of a model for predicting adverse drug reactions and events in older patients.

Purpose: Older people are at an increased risk of developing adverse drug reactions (ADR) and adverse drug events (ADE). This study aimed to develop and validate a risk prediction model (ADAPTiP) for ADR/ADE in older populations.

Methods: We used the adverse drug reactions in an Ageing PopulaTion (ADAPT) cohort (N = 798; 361 ADR-related admissions; 437 non-ADR-related admissions), a cross-sectional study designed to examine the prevalence and risk factors for ADR-related hospital admissions in patients aged ≥ 65 years.

Self-Bias and Self-Related Mentalizing are Unaltered in Adolescents with Autism.

Purpose: The self is a multidimensional concept that can be represented at a pre-reflective (first-order) level, at a deeper, reflective level (second-order), or even at a meta-level (representing one's own thoughts, i.e. self-related mentalizing).

Prevalence of co-occurring conditions among youths receiving treatment with primary anxiety, ADHD, or depressive disorder diagnoses.

Introduction: Anxiety disorders, depressive disorders, and attention-deficit/hyperactivity disorder (ADHD) are some of the most common conditions that youths (<18 years old) receive mental health treatment for. These conditions are associated with high-risk substance use or substance use disorders (SUDs). This study sought to identify the proportion of youths (<18 years old) with anxiety disorders, depressive disorders, or ADHD as a primary diagnosis in community mental health centers (CMHCs) having co-occurring high-risk substance use or a SUD.

Observation of the Protein-Inorganic Interface of Ferritin by Cryo-Electron Microscopy.

Visualizing the structure of the protein-inorganic interface is critically important for a more complete understanding of biomineralization. Unfortunately, there are limited approaches for the direct and detailed study of biomolecules that interact with inorganic materials. Here, we use single-particle cryo-electron microscopy (cryo-EM) to study the protein-nanoparticle (NP) interactions of human light chain ferritin and visualize the high-resolution details of the protein-inorganic interface.