Validity of A-Mode Ultrasound for Estimating Body Fat Percentage of Young Adult Athletes: A Multicomponent Model Study.

Purpose: This study compared %BFUS to %BF4C in young adult athletes.

Methods: University club sport athletes (86 women, 138 men) from a variety of teams participated. ADP, DXA, and bioimpedance spectroscopy were used to measure body volume, bone mineral content, and total body water, respectively, for the 4C model.

Iliosacral screw osteosynthesis - state of the art.

Iliosacral screw osteosynthesis is a widely recognized technique for stabilizing unstable posterior pelvic ring injuries, offering notable advantages, including enhanced mechanical stability, minimal invasiveness, reduced blood loss, and lower infection rates. However, the procedure presents technical challenges due to the complex anatomy of the sacrum and the proximity of critical neurovascular structures. While conventional fluoroscopy remains the primary method for intraoperative guidance, precise preoperative planning using multiplanar reconstructions and three-dimensional volume rendering is crucial for ensuring accurate placement of iliosacral or transsacral screws.

Provenance of late Pleistocene loess in central and eastern Europe: isotopic evidence for dominant local sediment sources.

Loess profiles along the Danube River provide a record of long-term Quaternary dust (loess) deposition in central-eastern Europe. Here, Sr-Nd isotopic data from four loess-palaeosol profiles (47 samples) spanning the last two-glacial-interglacial cycles are presented. The isotopic compositions generated by this study are compared with bedrock and sedimentary samples from Europe and North Africa to decipher the sources of sediment.

Activity and safety of avelumab in high-grade neuroendocrine tumors and poorly differentiated neuroendocrine carcinomas progressive after chemotherapy (AveNEC trial).

Background: Neuroendocrine neoplasias grade 3 (NEN G3) are rare tumors with poor prognosis and no established second-line therapy. The role of immune checkpoint blockade in these aggressive tumors remains unclear.

Methods: The phase II AVENEC study evaluated the effect of avelumab (AVE, 10 mg/kg IV Q2W) in 60 patients with well-differentiated high-grade neuroendocrine tumors (NET G3, N=22) or poorly differentiated neuroendocrine carcinomas (NEC, N=38) progressing after ≥ one prior chemotherapy (excluding Merkel cell and small-cell lung cancer).

Stuck in the Sump: A Rare Complication of Biliary Surgery.

Sump syndrome is a rare complication of biliary surgery that is now rarely seen in the era of Endoscopic Retrograde Cholangiopancreatography (ERCP). It occurs when the distal common bile duct becomes obstructed between an anastomosis from a choledochoduodenostomy (CDD) and the ampulla of Vater, forming a sump that accumulates debris. Sump syndrome should be considered as a diagnosis in patients who present with cholangitis or pancreatitis and any history of biliary diversion, regardless of the time of presentation.