Publications by authors named "D D Tshilanda"
Article Synopsis
- The essential oil (EO) from an African medicinal plant was analyzed and found to mainly contain benzyl isothiocyanate (96.23%), which exhibited significant insect antifeedant and nematicidal activities against various pests and root-knot nematodes.
- The oil effectively impacted insect feeding patterns, with specific efficient doses noted, while it showed potent activity against nematode juveniles and inhibited egg hatching significantly.
- While the EO suppressed germination and growth of ryegrass and reduced tomato root growth, it demonstrated selective effects on crops, indicating its potential use for sustainable pest control in agriculture.
SARS-CoV-2 is the pathogen agent of the new corona virus disease that appeared at the end of 2019 in China. There is, currently, no effective treatment against COVID-19. We report in this study a molecular docking study of ten molecules with the main protease (3CLpro) responsible for the replication of coronaviruses.
View Article and Find Full Text PDFEthnopharmacological Survey and Antisickling Activity of Plants Used in the Management of Sickle Cell Disease in Kikwit City, DR Congo.
Evid Based Complement Alternat Med
October 2020
Background: Sickle cell disease or drepanocytosis is the most known hemoglobin abnormality in the world. Recently, many medicinal plants used in the management of sickle cell disease in African traditional medicine have shown antisickling activity.
Objective: This research study aims to document some Congolese plant species used in the management of sickle cell disease in Kikwit city and investigate their pharmacological property .
The present study reports in vitro anti-sickling activity and phytochemical analyses of the leaves of Ocimum gratissimum. Biological testing revealed that the plant extracts possess antisickling effects. The combination of spectroscopic techniques: 1D-NMR, 2D-NMR and MS revealed that ursolic acid is the major biologically active compound of O.
View Article and Find Full Text PDFObjective: To perform phytochemical analyses on the leaves of Ocimum basilicum L. (O. basilicum), to elucidate the structure of isolate and then perform the antisickling activity on the crude extract and on the isolate.
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