Publications by authors named "D D Rockey"

Acute hemorrhagic rectal ulcer (AHRU) is a rare but potentially life-threatening condition. We present the case of a 74-year-old man who developed sudden massive hematochezia and hypotension during hospitalization for fever of unknown origin. He was known to have alcohol-related liver cirrhosis, hypoalbuminemia and coronary artery disease (CAD) and was on daily aspirin.

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A pancreatic fistula is defined as the leakage of pancreatic fluid into another organ or compartment because of pancreatic duct disruption or pseudocyst formation. It is most often seen in middle-aged men between 40 and 50, particularly in patients who have a history of chronic alcoholism and pancreatitis. The tract may fistulae into the pleura, creating a pancreaticopleural fistula, an exceedingly rare condition presenting as a recurrent pleural effusion and extremely high amylase levels, a key distinguishing factor in diagnosis.

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Since the Asian Pacific Association for the Study of the Liver (APASL) published guidelines on non-cirrhotic portal fibrosis/idiopathic portal hypertension in 2007, there has been a surge in new information, especially with the introduction of the term porto-sinusoidal vascular disorder (PSVD). Non-cirrhotic intra-hepatic causes of portal hypertension include disorders with a clearly identifiable etiology, such as schistosomiasis, as well as disorders with an unclear etiology such as non-cirrhotic portal fibrosis (NCPF), also termed idiopathic portal hypertension (IPH). This entity is being increasingly recognized as being associated with systemic disease and drug therapy, especially cancer therapy.

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Article Synopsis
  • * Researchers successfully deleted the incA gene in C. trachomatis and verified the gene's absence through genetic testing and microscopy, observing changes in cell behavior.
  • * The system also successfully deleted multiple virulence factor genes in different Chlamydia strains, showing promise for advancing genetic manipulation techniques in this bacterium.
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Article Synopsis
  • Serum alkaline phosphatase (ALP) is frequently tested in patients, but it lacks specific diagnostic value since it can originate from multiple tissues; this study explores causes of isolated elevated ALP levels without a clear reason.
  • A retrospective study at the Medical University of South Carolina looked at 260 adults with unexplained elevated ALP results and found that 57% of cases were linked to underlying malignancies, particularly related to the liver and bones.
  • The study highlights the importance of recognizing an isolated elevated ALP as potentially indicative of serious conditions, especially metastatic cancer, rather than just primary liver issues.
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