Publications by authors named "D D Rahn"
Purpose: Randomized trials have found that patients with locoregionally advanced p16+ oropharyngeal squamous cell carcinoma (OPSCC) do not benefit from treatment deintensification, even among favorable risk groups. Although various methods have been used to identify candidates for treatment deintensification, the optimal approach is unknown.
Methods And Materials: We conducted a multi-institutional cohort study of 444 patients with previously untreated p16+ OPSCC undergoing definitive radiation therapy with or without systemic therapy between 2009 and 2022.
Article Synopsis
- A grassroots environmental-justice organization in Kansas City studied the heightened air pollution exposure faced by residents living near the largest railyard in the U.S. and its impact on asthma rates.
- The researchers conducted a cross-sectional study using health data and environmental monitoring to analyze asthma encounters in relation to proximity to pollution sources like railyards and toxic facilities.
- Their findings showed that greater distances from railyards were significantly linked to lower asthma rates, with a 3km increase associated with a 26% decrease in overall asthma symptoms, highlighting important environmental health disparities.
Objective: Identify factors associated with persistent sexual dysfunction and pain 12-months postpartum in an underserved population.
Methods: Extending Maternal Care After Pregnancy (eMCAP) is a program addressing health needs/disparities of patients at risk for worse perinatal outcomes. Participants completed the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) and Urinary Distress Index (UDI-6) 12-months postpartum.
Importance: The optimal surgical repair of vaginal vault prolapse after hysterectomy remains undetermined.
Objective: To compare the efficacy and safety of 3 surgical approaches for vaginal vault prolapse after hysterectomy.
Design, Setting, And Participants: This was a multisite, 3-arm, superiority and noninferiority randomized clinical trial.
Background: As the muscular and connective tissue components of the vagina are estrogen responsive, clinicians may recommend vaginal estrogen to optimize tissues preoperatively and as a possible means to reduce prolapse recurrence, but long-term effects of perioperative intravaginal estrogen on surgical prolapse management are uncertain.
Objective: This study aimed to compare the efficacy of perioperative vaginal estrogen vs placebo cream in reducing composite surgical treatment failure 36 months after native tissue transvaginal prolapse repair.
Study Design: This was an extended follow-up of a randomized superiority trial conducted at 3 tertiary US sites.