Publications by authors named "D D Miceli"
Feline hypersomatotropism (HST) can develop in both diabetic and non-diabetic cats, but studies evaluating the prevalence of HST in cats without diabetes mellitus (DM) are lacking. The aims of the study were to evaluate circulating insulin-like growth factor 1 (IGF-1) in non-diabetic cats with chronic kidney disease (CKD), to assess whether there is a correlation between general test of renal function and IGF-1 concentration in cats with CKD, and to screen this population for the presence of HST. In this prospective study, one hundred fifty-four non-diabetic cats (n = 154) with CKD from referral centers in Buenos Aires (Argentina) were evaluated.
View Article and Find Full Text PDFFeline hypersomatotropism (HST) is typically associated with diabetes mellitus (DM), whereas HST without concurrent DM has only been reported in a few cases. Weight gain may be observed in cats with HST. The aims of this study were to evaluate circulating insulin-like growth factor-1 (IGF-1) in non-diabetic cats with overweight/obesity, to screen this population for the presence of HST, and to assess whether there is a correlation between body weight/body condition score (BCS) and serum IGF-1 concentration in overweight/obese cats.
View Article and Find Full Text PDFArticle Synopsis
- Acromegaly is a disorder caused by excess growth hormone (GH) and insulin-like growth factor-1 (IGF-1), leading to distinct physical changes and various health complications in both humans and cats.
- A literature review highlighted similarities and differences in how acromegaly manifests in these species, including craniofacial changes, joint issues, and cardiometabolic risks.
- Both species experience growth-related problems and associated diseases, but unique symptoms like human-specific skin conditions and different physical changes in cats distinguish their presentations.
The chiral topological superconductor, which supports propagating nontrivial edge modes while maintaining a gapped bulk, can be realized hybridizing a quantum-anomalous-Hall thin slab with an ordinary s-wave superconductor. We show that by sweeping the voltage bias in a normal-hybrid-normal double junction, the pattern of electric currents in the normal leads spans three main regimes. From single-mode edge-current quantization at low bias, to double-mode edge-current oscillations at intermediate voltages and up to diffusive bulk currents at larger voltages.
View Article and Find Full Text PDF