Pharmacological manipulation of liver fibrosis progression using novel HDAC6 inhibitors.

Chronic liver injury characterized by unresolved hepatitis leads to fibrosis, potentially progressing to cirrhosis and hepatocellular carcinoma. Effective treatments for halting or reversing liver fibrosis are currently lacking. This study investigates the potential of HDAC6 as a therapeutic target in liver fibrosis.

The "new" new normal: changes in telemedicine utilization since COVID-19.

Objective: To evaluate trends in telemedicine utilization overall and across clinical specialties, providing insights into its evolving role in health care delivery.

Study Design: This retrospective cross-sectional study analyzed 1.9 million telemedicine video visits from a large academic health care system in New York City between 2020 and 2023.

The role of generic cognitive skills: An empirical investigation into the association between generic and sport-specific cognitive skills and playing level in youth football.

Objectives: Tests of cognitive skills are increasingly used to identify talent in sports such as football, but there is so far little evidence to suggest that those tests are associated with sport-specific cognitive skills and performance. The aim of this study was to establish the degree to which tests of generic cognitive skills are associated with football-specific skill in youth football. Specifically, we (i) established the degree to which tests of generic cognitive skills are associated with sport-specific cognitive skills, and (ii) compared the associations between generic and sport-specific cognitive skills and the playing level of youth footballers.

A split decision based on vision: an empirical approach to classify short-distance sprinters with a vision impairment.

Athletes with vision impairment (VI) competing in track athletics typically compete in one of three 'classes' based on the severity of their VI. The creation of these classes, however, was arbitrary and not based on evidence. The aim of this study was to investigate the relationship between monocular visual acuity (VA) and sprinting performance in athletes with a VI to establish the optimal cut-off point(s) between competition classes.