StretchView - A Multi-Axial Cell-Stretching Device for Long-Term Automated Videomicroscopy of Living Cells.

Incorporating mechanical stretching of cells in tissue culture is crucial for mimicking (patho)-physiological conditions and understanding the mechanobiological responses of cells, which can have significant implications in areas like tissue engineering and regenerative medicine. Despite the growing interest, most available cell-stretching devices are not compatible with automated live-cell imaging, indispensable for characterizing alterations in the dynamics of various important cellular processes. In this work, StretchView is presented, a multi-axial cell-stretching platform compatible with automated, time-resolved live-cell imaging.

Thermoelectric and electrical properties of triple-conducting multicomponent oxides based on substituted barium cerate-zirconate.

Multicomponent oxides often have exceptional thermal stability and interesting electronic properties. The present work presents the thermoelectric and electrical properties of the Ba(ZrHfSnTiFe)O and Ba(ZrHfSnTiCoCeBiFeYZn)O multicomponent perovskites. Single-phase cubic perovskites were synthesized using the solid-state reaction method.

Long-Term Protective Immunity against Infection Induced by a Genetically Modified Live Vaccine.

Human monocytic ehrlichiosis, an emerging tick-borne disease, is caused by . Infections with the pathogen are also common in the canine host. Our previous studies demonstrated that functional disruption within the phage head-to-tail connector protein gene results in bacterial attenuation, creating a modified live attenuated vaccine (MLAV).

Nonlinear Heart Rate Variability Analysis for Sleep Stage Classification Using Integration of Ballistocardiogram and Apple Watch.

Purpose: Wearable or non-contact, non-intrusive devices present a practical alternative to traditional polysomnography (PSG) for daily assessment of sleep quality. Physiological signals have been known to be nonlinear and nonstationary as the body adapts to states of rest or activity. By integrating more sophisticated nonlinear methodologies, the accuracy of sleep stage identification using such devices can be improved.

Genetically modified live vaccine offers protective immunity against wild-type Anaplasma marginale tick-transmission challenge.

Anaplasma marginale is a tick-borne pathogen of cattle that causes bovine anaplasmosis in tropical and subtropical regions throughout the world. Killed vaccines derived from infected erythrocytes have been used for control of this disease with limited success. Recently, we described a targeted deletion mutation in the phage head-to-tail connector protein gene of A.