[Hypokalemic nephropathy from the chronic use of diuretics and laxatives].

The cases of two women with morphologically proved hypokalemic nephropathy related to chronic use of diuretics and purgatives are reported. The disease has been detected because of reduced urine quantity, increase of body mass and edema. The serum protein level is low.

[Rapidly progressing glomerulonephritis developing against a background of idiopathic nephrotic syndrome].

A case is presented of a woman with idiopathic nephrotic syndrome--mesangioproliferative glomerulonephritis who after a 7-year therapeutic remission developed a rapidly progressing (semilunar) glomerulonephritis with a severe nephrotic syndrome, arterial hypertension, anemia, renal failure. The patient was not influenced by the treatment with ordinary doses of glucocorticosteroids and temporarily improved by the combined "pulse" methylprednisolone, immunosuppressive and heparin treatment. The possible pathogenetic mechanisms which may have played a role in the transition of the idiopathic nephrotic syndrome into a rapidly progressing glomerulonephritis are discussed.

[An acute recurrence of focal-segmental glomerulosclerosis in a kidney transplanted from mother to son with a rapid decline in kidney function].

A case is presented of a 19-year-old man suffering from focal-segmental glomerulosclerosis with terminal chronic renal failure to whom a kidney taken from his mother was transplanted. There was high blood-group and tissue compatibility between mother and son. The initial result was good, the transplanted kidney functioned well-diuresis of 3300 ml with high proteinuria.

[Clinical, laboratory and morphological characteristics of mesangioproliferative glomerulonephritis].

The mesangioproliferative glomerulonephritis (MPGN) is the most frequent morphological type of primary glomerulonephritis and it was found in 42.7% of the patients studied. The MPGN is not a single nosologic entity which is proved by the immunofluorescent findings, clinical and laboratory characteristics.

[Acute recurrence of focal-segmental glomerulosclerosis in the kidney transplanted from mother to son with rapidly progressing failure of renal function].

After a brief survey, stressing upon the high susceptibility of the focal-segmental glomerulosclerosis to recurrences in transplated kidney, the authors announced one of their own observations on a youth, aged 19, that was transplated a kidney from a living donor--his mother. The basic disease in the acceptor led to chroniodialysis after 20 months of the first clinical signs. In spite of the high diuresis, that was observed after the transplantation of the maternal kidney, proteinuria persisted as early as the first days after the transplantation, creatinine did not reach the normal values and after I month chroniodialysis was again included, followed by detransplantation.