Publications by authors named "D Curran-Everett"
Rationale: Asthma severity in children generally starts mild but may progress and stay severe for unknown reasons.
Objectives: Identify factors in childhood that predict persistence of severe asthma in late adolescence and early adulthood.
Methods: The Childhood Asthma Management Program is the largest and longest asthma trial in 1041 children aged 5-12 years with mild to moderate asthma.
Article Synopsis
- Biofilm-associated infections in orthopedic surgery can lead to severe clinical complications and challenges in diagnosis, often resulting in ineffective antibiotic treatments due to bacteria's protective structures.
- Researchers explored the effects of a compound called MnTE-2-PyP, which is known to scavenge reactive species and modify the redox state, in treating these infections.
- In tests on a mouse model, combining MnTE-2-PyP with antibiotics significantly reduced bacterial counts in infected bone compared to antibiotics alone, suggesting that managing the redox environment can enhance antibiotic efficacy against biofilm-related infections.
Background: Neurovascular insult, nonunion, and iatrogenic rotator cuff injury are concerns when using an intramedullary nail (IMN) for proximal humerus fracture. The purpose of this study was to identify a reproducible starting point and intraoperative imaging for nail insertion optimizing nail depth, tuberosity screw position, and protecting the axillary nerve and rotator cuff insertion. Our hypothesis was that a more medialized starting point would protect soft tissue structures and improve locking screw positioning.
View Article and Find Full Text PDFObjectives: Prior work has shown substantial between-hospital variation in do-not-resuscitate orders, but stability of do-not-resuscitate preferences between hospitalizations and the institutional influence on do-not-resuscitate reversals are unclear. We determined the extent of do-not-resuscitate reversals between hospitalizations and the association of the readmission hospital with do-not-resuscitate reversal.
Design: Retrospective cohort study.