The use of reformatted Cone Beam CT images in assessing mid-face trauma, with a focus on the orbital floor fractures.

Background And Aim: This study aims at evaluating the reliability on specific multi-planar cone beam computer tomography (CBCT) reconstruction in the orbital floor fractures.

Methods: CBCT examination of the mid-face fractures area involving the floor of the orbit was performed in a number of 93 trauma patients by two independent radiologists. Both radiologists assessed the axial, coronal and sagittal sections and also the oblique coronal and sagittal extracted sections evaluating the location of the orbital fractures, its size and displacement, the involvement of the infra-orbital foramen, herniation of fat or muscle within the maxillary sinus, the overall type of the fracture and the implication of lateral or medial orbital wall.

Celiac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variation.

Background: Celiac disease (CD) is caused by an uncontrolled immune response to gluten, a heterogeneous mixture of wheat storage proteins. The CD-toxicity of these proteins and their derived peptides is depending on the presence of specific T-cell epitopes (9-mer peptides; CD epitopes) that mediate the stimulation of HLA-DQ2/8 restricted T-cells. Next to the thoroughly characterized major T-cell epitopes derived from the α-gliadin fraction of gluten, γ-gliadin peptides are also known to stimulate T-cells of celiac disease patients.