Publications by authors named "D Coustou"

Background: The frequency of dermatological acts is increasing. These procedures often cause injuries and traumatic alterations in specific skin layers, slowing down wound healing.

Patients And Methods: An open observational study lasting 1 month was conducted on 2,363 patients who had undergone various dermatological procedures.

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The skin is the largest organ of the body, providing a protective barrier against bacteria, chemicals and physical insults while maintaining homeostasis in the internal environment. Such a barrier function the skin ensures protection against excessive water loss. The skin's immune defence consists of several facets, including immediate, non-specific mechanisms (innate immunity) and delayed, stimulus-specific responses (adaptive immunity), which contribute to fending off a wide range of potentially invasive microorganisms.

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Background: The efficacy of topical antifungals is controversial.

Objective: To compare the efficacy and safety of a sequential(SEQ) treatment with chemical nail avulsion and topical antifungals to amorolfine nail lacquer in dermatophytic onychomycosis.

Methods: This was a randomized,parallel-group, controlled study comparing a 36-week SEQ treatment with chemical nail avulsion with RV4104A ointment(class I medical device containing 40% urea) followed by ciclopirox cream for 8 weeks and ciclopirox nail lacquer for 25 weeks (SEQ group) to amorolfine nail lacquer for 36 weeks (AMO group).

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Article Synopsis
  • This study aimed to investigate potential causes of asymmetrical periflexural exanthem of childhood (APEC) by examining various microbiological agents through a case-control approach.
  • Researchers analyzed samples from 37 children with APEC and 37 age-matched controls but found no significant differences in the presence of viruses or bacteria between the two groups.
  • The results suggested that APEC is not triggered by common microbiological agents, indicating the need for more advanced methods to explore its underlying causes.
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