Publications by authors named "D Cotton"

Control over CO capture and utilization are important scientific and technological challenges. Although a variety of amine absorbents are used for capture, releasing the captured CO is often difficult and limits their recyclability. Therefore, it is crucial to control the strength of the CO bond with the absorbent.

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Article Synopsis
  • The study investigates the rising cases of cannabinoid hyperemesis syndrome (CHS) in emergency departments in Northern California over an 11-year period, correlating with increased cannabis access.
  • It utilized electronic health records to identify adults experiencing CHS symptoms, focusing on two different case definitions that required a primary diagnosis of vomiting.
  • Results showed a significant increase in suspected CHS cases, with a 134-175% rise in annual prevalence, especially notable in the stricter case definition, suggesting that changes in medical coding may have influenced these estimates.
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Capturing carbon dioxide (CO) from the atmosphere is a scientific and technological challenge. CO can be captured by forming carbamate bonds with amines, most notably monoethanolamine (MEA). Regenerating MEA by releasing captured CO requires that the carbamate solution be heated.

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Aims: The aim of this work is to compare empagliflozin systemic exposure between patients with heart failure (HF) and patients with type 2 diabetes (T2D).

Methods: Analysis of covariance (ANCOVA) compared steady state trough concentrations of empagliflozin 10 mg in EMPEROR-reduced (patients with HF with reduced ejection fraction [HFrEF]) and EMPA-REG OUTCOME (patients with T2D at high cardiovascular risk) after adjusting for eGFR and body weight.

Results: The difference in geometric Mean (gMean) empagliflozin steady state trough concentration of 10 mg empagliflozin between EMPEROR-reduced and EMPA-REG OUTCOME was 1.

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