Publications by authors named "D Costea"

Breast cancer still represents the most commonly diagnosed cancer among women, accounting for 12.5% of all new annual cancer cases worldwide. In Romania in 2020, breast cancer was the most common, with a share of new cases of 26.

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Background: Survival rate of patients with oral cancer (OC) remains to be very low despite advancements in therapy and surgical techniques. This is attributed to the fact that most OC cases are discovered at a late stage. Dentists play a vital role in early detection of OC through oral mucosal examination, and in informing the patients about avoidable risk factors of the disease, such as tobacco and excessive alcohol use.

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  • Parkinson's disease is a neurodegenerative condition that often includes psychiatric symptoms like anxiety and depression in over 60% of patients, leading to a high risk of impulse control disorders (ICDs) such as compulsive shopping and gambling.
  • A study conducted over six years explored pharmacological treatments for ICDs among Parkinson's patients, using the Hamilton Rating Scale to evaluate their symptoms and outcomes.
  • The results showed a reduction in impulsive behaviors among patients, and the article discusses potential future research directions to further address these symptoms.
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Skin malignant melanoma (MM) is one of the most frequent and aggressive neoplasia worldwide. Its associated high mortality rates are mostly due to its metastases, while diagnosis and treatment of MM in its early stages is of favorable prognostic. Even skin superficial MMs at incipient local stages can already present with lymph node invasion and distant metastases.

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  • Traumatic brain injury (TBI) and spinal cord injury (SCI) are serious conditions caused by physical damage and inflammation, leading to additional problems like slow-healing skin wounds.
  • Researchers studied a special protein called FGF-2, which might help with recovery by supporting brain and skin cell healing.
  • They created tiny particles (called FGF-ELP) that protect nerve cells and help skin cells grow and heal, showing promise for treating injuries.
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