Publications by authors named "D Coso"
Background: Latreille, 1796 is a small genus of the dead log bark beetles (Coleoptera, Pythidae). All species are distributed in the Holarctic, being recognised as typically boreal taxa, but knowledge about the geographical ranges of particular taxa is far from complete.
New Information: The updated distributional checklist of the genus of the Palearctic is given, based on literature and new records, including citizen-scientific data.
Article Synopsis
- * 32 patients were treated with a combination of Rituximab and Lenalidomide (R2) over a median follow-up of 22.6 months, but the treatment only achieved a 12.5% response rate.
- * The results showed a median progression-free survival of 2.6 months and a median overall survival of 9.3 months, leading researchers to conclude that the R2 regimen is not advisable for high-risk patients in this group.
Purpose: The AHL2011 study (ClinicalTrials.gov identifier: NCT01358747) demonstrated that a positron emission tomography (PET)-driven de-escalation strategy after two cycles of bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone (BEACOPP) provides similar progression-free survival (PFS) and overall survival (OS) and reduces early toxicity compared with a nonmonitored standard treatment. Here, we report, with a prolonged follow-up, the final study results.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to understand the molecular changes that occur as lymphomatoid papulosis (LyP) evolves into cutaneous anaplastic large-cell lymphoma (c-ALCL) and lymph node invasion (LNI).
- Researchers analyzed nine tumors from a single patient who experienced both LyP and c-ALCL along with other types of lymphoma, finding a common T-cell origin for the CD30+ lesions and a common B-cell origin for diffuse large B-cell lymphoma (DLBCL).
- They concluded that the evolution from LyP to c-ALCL and LNI represents a progressive clonal evolution from a shared precursor, suggesting that nodal ALCL should be viewed as a transformation rather than a separate entity
Bendamustine-based conditioning prior to autologous stem cell transplantation (ASCT): Results of a French multicenter study of 474 patients from LYmphoma Study Association (LYSA) centers.
Am J Hematol
June 2018
Carmustine shortage has led to an increase use of alternative conditioning regimens prior to autologous stem cell transplantation for the treatment of lymphoma, including Bendamustine-based (BeEAM). The aim of this study was to evaluate the safety of the BeEAM regimen in a large cohort of patients. A total of 474 patients with a median age of 56 years were analyzed.
View Article and Find Full Text PDF