Publications by authors named "D Coskun"
Article Synopsis
- Danofloxacin, a fluoroquinolone antibiotic, is effective against bacterial infections in fish, but its pharmacokinetics vary based on fish size, impacting its medicinal effectiveness.!* -
- A study conducted on rainbow trout demonstrated that larger fish have higher plasma concentrations and overall drug efficacy of danofloxacin compared to smaller fish, with measurements taken after oral administration.!* -
- While larger fish show increased therapeutic efficacy, their higher drug concentrations in tissues raise concerns about potential residue and withdrawal time for safe consumption.!*
Autism spectrum disorder is a neurodevelopmental disorder in which learning, communication, and social interaction are impaired. Research has sought to minimize the neural impairments associated with autism spectrum disorder and improve the quality of life. Recent studies suggest that boron may benefit nerve cells, with effects varying depending on the dosage.
View Article and Find Full Text PDFObjective: This study aimed to investigate the plasma and milk pharmacokinetics, as well as the withdrawal time (WT) from milk of tolfenamic acid (2 and 4 mg/kg) following intravenous (IV) administration to eight healthy lactating Akkaraman sheep.
Methods: The trial was conducted in two periods in accordance with a crossover pharmacokinetic design. The concentrations of tolfenamic acid in the plasma and milk were determined using high-pressure liquid chromatography and evaluated using non-compartmental analysis.