Publications by authors named "D Coletti"

Background: POCUS is valuable in primary care, yet outpatient-specific point-of-care ultrasound (POCUS) curriculum integration into internal medicine (IM) residency is limited. We addressed this gap by developing a thyroid POCUS workshop for IM residents.

Aim: Develop and implement an educational curriculum to integrate thyroid POCUS into an IM residency program and evaluate the impact on resident knowledge, perceived skills, and attitudes.

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Only in recent years, thanks to a precision medicine-based approach, have treatments tailored to the sex of each patient emerged in clinical trials. In this regard, both striated muscle tissues present significant differences between the two sexes, which may have important consequences for diagnosis and therapy in aging and chronic illness. In fact, preservation of muscle mass in disease conditions correlates with survival; however, sex should be considered when protocols for the maintenance of muscle mass are designed.

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Article Synopsis
  • * Research shows that blocking HDACs with pan-HDAC inhibitors (like givinostat) can improve muscle structure and function in conditions such as Duchenne Muscular Dystrophy (DMD), with promising results from clinical trials.
  • * The review highlights how HDACs influence muscle cell behavior and could lead to better treatment strategies for muscular dystrophies by targeting their roles in muscle repair and regeneration.
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